BDBM591041 US11566003, Compound 127::trans-N-(8-amino-6-((S)-4-methyl-2- oxooxazolidin-3-yl)isoquinolin-3- yl)-2-cyanocyclopropane-1- carboxamide

SMILES C[C@H]1COC(=O)N1c1cc(N)c2cnc(NC(=O)[C@@H]3C[C@H]3C#N)cc2c1

InChI Key InChIKey=ZTBXUVMQQSWDSG-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 591041   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM591041(trans-N-(8-amino-6-((S)-4-methyl-2- oxooxazolidin-...)Copy SMILESCopy InChI

Affinity DataKi:  0.0520nMAssay Description:For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. The solut...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/19/2023
Entry Details
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