BDBM590268 US11560385, Compound 41B

SMILES Cc1nc(Cc2cc(C(=O)CN3C4CCC3[C@@H](O)C4)c(C)n2-c2ccc(cc2)C#N)cs1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590268   

TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590268(US11560385, Compound 41B)
Affinity DataIC50: 50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent