BDBM590228 US11560385, Compound 4B

SMILES Cc1c(cc(C[C@H]2C[C@H](C2)C#N)n1-c1ccc(cc1)C#N)C(=O)CN1C2CCC1[C@@H](O)C2

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 590228   

TargetUbiquitin carboxyl-terminal hydrolase 14(Human)
Proteostasis Therapeutics

US Patent
LigandPNGBDBM590228(US11560385, Compound 4B)
Affinity DataIC50: 50nMAssay Description:Usp14 Inhibition Assay was described in B. H. Lee et al. Nature 2010, 467 (9), 179.More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent