BDBM589895 US11559538, Example 147::US11559538, Example 148

SMILES CCCOc1cc(ccc1OC)-c1nc(ns1)C1COB(O)C1

InChI Key InChIKey=LBADOWKZXSXFPE-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 589895   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of human PDE4 catalytic domain expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 0.440nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 1.26E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 2.69nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 1.57nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 0.240nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 759nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 4.92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589895(US11559538, Example 147 | US11559538, Example 148)
Affinity DataIC50: 1.68nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent