BDBM589837 US11559538, Example 91::US11559538, Example 92

SMILES CCOc1cc(-c2nc(cs2)C2COB(O)C2)c(F)cc1OC

InChI Key InChIKey=ZCXIXFCQEYNXGY-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589837   

LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 3nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 460nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 5.90nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 3.92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 1.79nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 947nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 3.36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589837(US11559538, Example 91 | US11559538, Example 92)
Affinity DataIC50: 2.70nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent