BDBM589825 US11559538, Example 81::US11559538, Example 82

SMILES CCCOc1c(OC)ccc(c1F)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=MANABQSIOLMRPG-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589825   

LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 2.36nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 858nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 54.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 1.62nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 0.550nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 426nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 7.14nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589825(US11559538, Example 81 | US11559538, Example 82)
Affinity DataIC50: 1.07nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent