BDBM589802 US11559538, Example 194::US11559538, Example 58

SMILES CCOc1cc(ccc1OC)-c1nc(cs1)C1COB(O)C1

InChI Key InChIKey=DOHGXEYAJKNMEM-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589802   

LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 3.63nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 1.54E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 2.85nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 14.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 0.720nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 103nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 163nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589802(US11559538, Example 58 | US11559538, Example 194)
Affinity DataIC50: 1.81nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent