BDBM589801 US11559538, Example 57::US11559538, Example 76

SMILES CCCOc1cc(ccc1OC)-c1nc(CO)cc(n1)C1COB(O)C1

InChI Key InChIKey=GKCOMAYJFHLWPF-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589801   

LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 10.2nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 239nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 7.54nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 2.29nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 10nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 403nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 5.75nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589801(US11559538, Example 57 | US11559538, Example 76)
Affinity DataIC50: 2.17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent