BDBM589760 US11559538, Example 124::US11559538, Example 23::US11559538, Example 55

SMILES CCCOc1cc(ccc1OC)-c1nc(cc(n1)C(F)(F)F)C1COB(O)C1

InChI Key InChIKey=DBYHADKMRHGYGR-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589760   

LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 2.20nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 1.66E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 9.48nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 10.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 0.970nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 132nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 0.610nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 0.850nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 2.21nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 576nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 3.94nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589760(US11559538, Example 23 | US11559538, Example 124 |...)
Affinity DataIC50: 2.27nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent