BDBM589755 US11559538, Example 18::US11559538, Example 51

SMILES CCCOc1cc(cnc1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=JXNIBNDOFRIIAK-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589755   

LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 0.740nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 218nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 1.91nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 2.23nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 1.27nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 337nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 3.73nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589755(US11559538, Example 18 | US11559538, Example 51)
Affinity DataIC50: 1.64nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent