BDBM589754 US11559538, Example 17::US11559538, Example 50

SMILES CCCOc1cc(ccc1OC(F)F)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=OWOCAAPJLVDNFW-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 589754   

LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 0.280nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 138nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 0.650nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 0.470nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 0.790nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 234nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 1.04nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589754(US11559538, Example 17 | US11559538, Example 50)
Affinity DataIC50: 1.52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent