BDBM589748 US11559538, Example 12::US11559538, Example 214::US11559538, Example 44

SMILES CCOc1cc(cc(F)c1OC)-c1cncc(c1)C1COB(O)C1

InChI Key InChIKey=VGMJYZGTXNEQDA-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 589748   

LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 4.92nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 2.00E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 20.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 13.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 1.08nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 162nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 2.32nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 0.990nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 2.5nMAssay Description:Cytokine inhibitory activity is determined by measuring the effect of test agent on the release of the cytokines IL-4, IL-13 and IFNγ from human...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-13(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 167nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterleukin-4(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 7.22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetInterferon gamma receptor 1(Human)
Pfizer

US Patent
LigandPNGBDBM589748(US11559538, Example 12 | US11559538, Example 44 | ...)
Affinity DataIC50: 1.34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent