BDBM589245 US11554172, Compound 19

SMILES C[C@@H]1C[C@H]2[C@@H]3C[C@H](F)C4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]2(C)[C@@]1(OC(=O)CCCCCP(O)(O)=O)C(=O)SCF

InChI Key InChIKey=HXGFMAQEKRLSND-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 589245   

TargetGlucocorticoid receptor(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM589245(US11554172, Compound 19)
Affinity DataIC50: 0.140nMAssay Description:The potency of binding to gucocorticoid receptor by small molecule compounds was measured with the PolarScreen Glucocorticoid Receptor Competitor Ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2023
Entry Details
Go to US Patent