BDBM588599 US11542293, Compound I-46

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@H](C[C@@H](Nc4ccncn4)[C@@H]3F)COP(O)(=O)O[C@@H]1[C@@H]2O

InChI Key InChIKey=SVSIICXWCSTPNK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588599   

TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM588599(US11542293, Compound I-46)
Affinity DataIC50: 1.00E+3nMAssay Description:40 nL of test compounds in DMSO were added to wells in a white, 384 well microtitre plate (Greiner 784075). 2 uL STING assay buffer (PBS and 0.01% BS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent