BDBM588592 2-amino-9-{(2S,5R,7R,8R,10S,12aR,14R,15aS,16R)-16-hydroxy-2,10-dioxido-14- [(6-oxo-1,6-dihydropyrimidin-4-yl)amino]-2,10-disulfanyldecahydro-5,8- methanocyclopenta[1][1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecin-7-yl}- 1,9-dihydro-6H-purin-6-one::US11542293, Compound I-41a::US11542293, Compound I-41b

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)O[C@H]3C[C@@H](C[C@@H]3COP(S)(=O)O[C@@H]1[C@@H]2O)Nc1cc(=O)[nH]cn1

InChI Key InChIKey=ONKUSUZRXGVHKS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588592   

TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM588592(2-amino-9-{(2S,5R,7R,8R,10S,12aR,14R,15aS,16R)-16-...)
Affinity DataIC50: 5.50E+3nMAssay Description:40 nL of test compounds in DMSO were added to wells in a white, 384 well microtitre plate (Greiner 784075). 2 uL STING assay buffer (PBS and 0.01% BS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM588592(2-amino-9-{(2S,5R,7R,8R,10S,12aR,14R,15aS,16R)-16-...)
Affinity DataIC50: 5.50E+3nMAssay Description:40 nL of test compounds in DMSO were added to wells in a white, 384 well microtitre plate (Greiner 784075). 2 uL STING assay buffer (PBS and 0.01% BS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent