BDBM588536 2-amino-9-{(5R,7R,8R,12aR,14R,15S,15aR,16R)-14-[(5-fluoropyrimidin-4-yl) amino]-2,10,15,16-tetrahydroxy-2,10-dioxidodecahydro-5,8-methanocyclopenta[1] [1,3,6,9,11,2,10]pentaoxadiphosphacyclotetradecin-7-yl}-1,9-dihydro-6H-purin-6- one::US11542293, Compound I-8

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=O)O[C@@H]3[C@H](C[C@@H](Nc4ncncc4F)[C@@H]3O)COP(O)(=O)O[C@@H]1[C@@H]2O

InChI Key InChIKey=IRDVGKPKKXEBHY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588536   

TargetStimulator of interferon genes protein(Human)
Takeda Pharmaceutical

US Patent
LigandPNGBDBM588536(2-amino-9-{(5R,7R,8R,12aR,14R,15S,15aR,16R)-14-[(5...)
Affinity DataIC50: 5.50E+3nMAssay Description:40 nL of test compounds in DMSO were added to wells in a white, 384 well microtitre plate (Greiner 784075). 2 uL STING assay buffer (PBS and 0.01% BS...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent