BDBM588478 (R)-N-(2,5-dichlorobenzoyl)-3- methylmercaptopropionamido-D-leucine boric acid::US11542283, Compound IV-9

SMILES CSC[C@H](NC(=O)c1cc(Cl)ccc1Cl)C(=O)N[C@@H](CC(C)C)B(O)O

InChI Key InChIKey=QFAAHRPOEKMFBC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588478   

TargetProteasome subunit alpha type-6(Human)
Jiangsu Chia Tai Fenghai Pharmaceutical

US Patent
LigandPNGBDBM588478(US11542283, Compound IV-9 | (R)-N-(2,5-dichloroben...)
Affinity DataIC50: 4.86nMAssay Description:The proteasome used in the present invention is human erythrocyte 20S proteasome, and the enzyme, fluorescent substrate and test buffer are all purch...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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