BDBM588437 US11542275, Compound 59

SMILES COc1cc(ccn1)-c1ccc(CN2CCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)nc1

InChI Key InChIKey=QUCDTSOCSVJADS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588437   

TargetProtein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588437(US11542275, Compound 59)
Affinity DataIC50: 25nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent