BDBM588403 US11542275, Compound 25

SMILES O[C@@H](CN1CCN(Cc2ccc(nc2)N2C3CCC2CC(F)(F)C3)C1=O)CN1CCc2ccccc2C1

InChI Key InChIKey=UVOREDQGCCMTKD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588403   

TargetProtein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588403(US11542275, Compound 25)
Affinity DataIC50: 36nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent