BDBM588398 US11542275, Compound 20

SMILES C[C@H]1CN(C[C@@H](C)N1C(C)=O)c1ccc(CN2CCN(C[C@H](O)CN3CCc4ccccc4C3)C2=O)nc1

InChI Key InChIKey=PRPWZDFVEDGRNM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588398   

TargetProtein arginine N-methyltransferase 5(Human)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM588398(US11542275, Compound 20)
Affinity DataIC50: 31nMAssay Description:Protein arginine methyltransferase 5 (PRMT5) is a type II arginine methyltransferase that catalyze mono- and symmetric demethylation on arginine resi...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
US Patent