BDBM588205 4-(3-((S)-3-Ethyl-4-(4'-fluoro-6- (((S)-pyrrolidin-1-ium-3-yl)oxy)- [1,1'-biphenyl]-3-carbonyl) piperazine-1-carbonyl)-5- fluorophenyl)piperazin-1-ium chloride::US11542254, Example 63

SMILES CC[C@H]1CN(CCN1C(=O)c1ccc(O[C@H]2CC[NH2+]C2)c(c1)-c1ccc(F)cc1)C(=O)c1cc(F)cc(c1)N1CC[NH2+]CC1

InChI Key InChIKey=IHIZQEYRIXQPEC-UHFFFAOYSA-P

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 588205   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588205(4-(3-((S)-3-Ethyl-4-(4'-fluoro-6- (((S)-pyrrolidin...)
Affinity DataKi:  1.00E+4nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent