BDBM588184 S)-(4-(3-Fluoro-5-(piperazin-1-yl) benzoyl)piperazin-1-yl)(4'-fluoro- 6-(pyrrolidin-3-yloxy)-[1,1'- biphenyl]-3-yl)methanone hydrochloride::US11542254, Example 2::US11542254, Example 8

SMILES Fc1ccc(cc1)-c1cc(ccc1O[C@H]1CC[NH2+]C1)C(=O)N1CCN(CC1)C(=O)c1cc(F)cc(c1)N1CC[NH2+]CC1

InChI Key InChIKey=LXPIWIDLDOAJGK-UHFFFAOYSA-P

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588184   

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588184(S)-(4-(3-Fluoro-5-(piperazin-1-yl) benzoyl)piperaz...)
Affinity DataKi:  1.90E+4nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetCatenin beta-1/B-cell CLL/lymphoma 9 protein(Human)
Universisity of Utah Research Foundation

US Patent
LigandPNGBDBM588184(S)-(4-(3-Fluoro-5-(piperazin-1-yl) benzoyl)piperaz...)
Affinity DataKi:  2.00E+4nMAssay Description:Alphascreen Assays to Determine the Apparent Kd Values for Wild-Type and Mutant β-Catenin/BCL9 InteractionsThe experimental detail using AlphaSc...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent