BDBM588176 1-[4-[[5-[2-(3- chloroanilino)pyrimidin- 5-yl]-3-pyridyl]amino]-2- methyl-1- pipendyl]prop-2-en-1- one::US11542249, Example 47

SMILES CC1CC(CCN1C(=O)C=C)Nc1cncc(c1)-c1cnc(Nc2cccc(Cl)c2)nc1

InChI Key InChIKey=ATMFHXVIDXPYGK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588176   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588176(1-[4-[[5-[2-(3- chloroanilino)pyrimidin- 5-yl]-3-p...)
Affinity DataIC50: 6.70nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588176(1-[4-[[5-[2-(3- chloroanilino)pyrimidin- 5-yl]-3-p...)
Affinity DataIC50: 6.10E+3nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent