BDBM588169 1-[3-[[6-[2-[(6- methyl-2- pyridyl)amino] pyrimidin-5-yl] pyrazin-2- yl]amino]azetidin- 1-yl]prop-2-en-1- one::US11542249, Example 40

SMILES Cc1cccc(Nc2ncc(cn2)-c2cncc(NC3CN(C3)C(=O)C=C)n2)n1

InChI Key InChIKey=QEQNNNIWUVRTRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588169   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588169(1-[3-[[6-[2-[(6- methyl-2- pyridyl)amino] pyrimidi...)
Affinity DataIC50: 5.58nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588169(1-[3-[[6-[2-[(6- methyl-2- pyridyl)amino] pyrimidi...)
Affinity DataIC50: 54.9nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent