BDBM588149 1-[4-[[5-[2-[[6- (trifluoromethyl)-2- pyridyl]amino] pyrimidin-5-yl]-3- pyridyl]amino]-1- piperidyl]prop-2-en-1- one::US11542249, Example 21

SMILES FC(F)(F)c1cccc(Nc2ncc(cn2)-c2cncc(NC3CCN(CC3)C(=O)C=C)c2)n1

InChI Key InChIKey=PMXNWPXKACGRLT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588149   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588149(1-[4-[[5-[2-[[6- (trifluoromethyl)-2- pyridyl]amin...)
Affinity DataIC50: 8.84nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588149(1-[4-[[5-[2-[[6- (trifluoromethyl)-2- pyridyl]amin...)
Affinity DataIC50: 1.00E+5nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent