BDBM588148 1-[4-[[5-[2-[(6-methyl-2-pyridyl)amino]pyrimidin-5-yl]-3-pyridyl]amino]-1-piperidyl]prop-2-en-1-one::US11542249, Example 20

SMILES Cc1cccc(Nc2ncc(cn2)-c2cncc(NC3CCN(CC3)C(=O)C=C)c2)n1

InChI Key InChIKey=VLHFOKDPBILTQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588148   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588148(1-[4-[[5-[2-[(6-methyl-2-pyridyl)amino]pyrimidin-5...)
Affinity DataIC50: 16.9nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588148(1-[4-[[5-[2-[(6-methyl-2-pyridyl)amino]pyrimidin-5...)
Affinity DataIC50: 2.22E+3nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent