BDBM588145 1-{(3S)-3-[(5-{2-[(6- methylpyridin-2- yl)amino]pyrimidin-5- yl}pyridin-3- yl)amino]pyrrolidin-1- yl}prop-2-en-1-one::US11542249, Example 17

SMILES Cc1cccc(Nc2ncc(cn2)-c2cncc(N[C@H]3CCN(C3)C(=O)C=C)c2)n1

InChI Key InChIKey=FGETUARTQMINCJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588145   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588145(1-{(3S)-3-[(5-{2-[(6- methylpyridin-2- yl)amino]py...)
Affinity DataIC50: 32.9nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588145(1-{(3S)-3-[(5-{2-[(6- methylpyridin-2- yl)amino]py...)
Affinity DataIC50: 1.61E+4nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent