BDBM588124 1-[3-[[5-[2-(3-chloro- 2-fluoro- phenoxy)pyrimidin-5- yl]-3- pyridyl]amino]azetidin- 1-yl]prop-2-en-1-one::US11542249, Example 2

SMILES Fc1c(Cl)cccc1Oc1ncc(cn1)-c1cncc(NC2CN(C2)C(=O)C=C)c1

InChI Key InChIKey=GWAOULQEDOVPRJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588124   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588124(1-[3-[[5-[2-(3-chloro- 2-fluoro- phenoxy)pyrimidin...)
Affinity DataIC50: 6.89nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
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TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588124(1-[3-[[5-[2-(3-chloro- 2-fluoro- phenoxy)pyrimidin...)
Affinity DataIC50: 121nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent