BDBM588123 1-[4-[[5-[2-(3-chlorophenoxy)pyrimidin-5-yl]-3-pyridyl]amino]-1-piperidyl]prop-2-en-1-one::US11542249, Example 1

SMILES Clc1cccc(Oc2ncc(cn2)-c2cncc(NC3CCN(CC3)C(=O)C=C)c2)c1

InChI Key InChIKey=ZXCOGFIILJJHFQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 588123   

TargetTyrosine-protein kinase BTK(Human)
Eli Lilly

US Patent
LigandPNGBDBM588123(1-[4-[[5-[2-(3-chlorophenoxy)pyrimidin-5-yl]-3-pyr...)
Affinity DataIC50: 25.3nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
Eli Lilly

US Patent
LigandPNGBDBM588123(1-[4-[[5-[2-(3-chlorophenoxy)pyrimidin-5-yl]-3-pyr...)
Affinity DataIC50: 470nMAssay Description:The BTK and EGFR biochemical assays utilize LANTHASCREEN Eu Kinase Binding Assays from Thermo Fisher Scientific, measuring the binding of the kinase ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/26/2023
Entry Details
Go to US Patent