BDBM587886 US11535621, Example 136

SMILES CO[C@H]1CC[C@@H](CC1)NC(=O)c1nc(nc2ccsc12)-n1ccnc1

InChI Key InChIKey=ZHOQOWJYXCWPRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 587886   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587886(US11535621, Example 136)
Affinity DataIC50: 10nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent