BDBM587747 US11535621, Example 8

SMILES COCCO[C@H]1CC[C@@H](CC1)NC(=O)c1cc(cc2cn[nH]c12)-n1ccnc1

InChI Key InChIKey=HICGGWXCFJIXDR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 587747   

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587747(US11535621, Example 8)
Affinity DataIC50: 550nMAssay Description:The CD38 enzyme assay was performed as described previously (Becherer, J D, et al. J. Med. Chem. 2015, 58, 7021-7056). Briefly, 200 nL of a dose resp...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent

TargetADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1(Human)
Ribon Therapeutics

US Patent
LigandPNGBDBM587747(US11535621, Example 8)
Affinity DataIC50: 21nMAssay Description:Inhibition of human his tagged CD38 using N6-etheno-NAD as substrate by fluorescence microplate reader assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
6/23/2023
Entry Details
PubMed