BDBM587560 N-hydroxy-2-(oxazolo[4,5-b]pyridin-2- yl)isoindoline-4-carboxamide::US11535607, Example 5-1

SMILES ONC(=O)c1cccc2CN(Cc12)c1nc2ncccc2o1

InChI Key InChIKey=YOHPTEYOXPEINU-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 587560   

TargetHistone deacetylase 11(Human)
Valo Health

US Patent
LigandPNGBDBM587560(N-hydroxy-2-(oxazolo[4,5-b]pyridin-2- yl)isoindoli...)
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
2/20/2023
Entry Details
Go to US Patent