BDBM587503 US11535596, Compound Dimemorfan (DIM)

SMILES CN1CC[C@@]23CCCC[C@@H]2[C@@H]1Cc1ccc(C)cc31

InChI Key InChIKey=KBEZZLAAKIIPFK-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 587503   

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandChemical structure of BindingDB Monomer ID 587503BDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataKi:  371nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetSigma non-opioid intracellular receptor 1(Human)
Center For Neurologic Study

US Patent
LigandChemical structure of BindingDB Monomer ID 587503BDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 527nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetSodium-dependent noradrenaline transporter(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 587503BDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 1.22E+3nMAssay Description:Inhibition of human NETMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 587503BDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 2.96E+3nMAssay Description:Inhibition of human GluN1/GluN2A NMDA receptor expressed in HEK293 cells assessed as reduction in glutamate induced current at -70 mV holding potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed
TargetGlutamate receptor ionotropic, NMDA 1(Human)
Center For Neurologic Study

US Patent
LigandChemical structure of BindingDB Monomer ID 587503BDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 3.00E+4nMAssay Description:In vitro binding assays for the phencyclidine site of NMDA-type glutamate receptors, and for sigma-1 receptors, both of which are known to be bound b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2023
Entry Details
US Patent

TargetSodium-dependent serotonin transporter(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 587503BDBM587503(US11535596, Compound Dimemorfan (DIM))
Affinity DataIC50: 1.48E+5nMAssay Description:Inhibition of human SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details
PubMed