BDBM585807 US11530229, Compound 22

SMILES CN(Cc1cc2C(=O)N(Cc2c(c1)C(F)(F)F)c1cccc(c1)[C@@]1(Cc2nncn2C)C[C@@H](C1)C#N)C1CC(F)(F)C1

InChI Key InChIKey=PWWQDUDRPWVFFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585807   

LigandPNGBDBM585807(US11530229, Compound 22)
Affinity DataIC50: 3.5nMAssay Description:The ability of candidate compounds to displace a known inhibitor and thereby inhibit Cbl-b activity was measured by monitoring the interaction of Cbl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2023
Entry Details
US Patent