BDBM585336 5-(4-(4-methoxyphenyl)piperazin-1-yl)pyrimidine-2,4-diamine::US11530198, Example 114

SMILES COc1ccc(cc1)N1CCN(CC1)c1cnc(N)nc1N

InChI Key InChIKey=MRBSMYAOELTSKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585336   

TargetDihydrofolate reductase(Human)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585336(US11530198, Example 114 | 5-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 813nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
Go to US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585336(US11530198, Example 114 | 5-(4-(4-methoxyphenyl)pi...)
Affinity DataIC50: 5.62nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
Go to US Patent