BDBM585298 5-(4-([1,1'-biphenyl]-3-yl)-3- methylpiperazin-1- yl)pyrimidine-2,4-diamine::US11530198, Example 26

SMILES CC1CN(CCN1c1cccc(c1)-c1ccccc1)c1cnc(N)nc1N

InChI Key InChIKey=VHMYOPZWBVDKAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 585298   

TargetDihydrofolate reductase(Human)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585298(US11530198, Example 26 | 5-(4-([1,1'-biphenyl]-3-y...)
Affinity DataIC50: 30.2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
Go to US Patent

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Vyera Pharmaceuticals

US Patent
LigandPNGBDBM585298(US11530198, Example 26 | 5-(4-([1,1'-biphenyl]-3-y...)
Affinity DataIC50: 2nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
Go to US Patent