BDBM585274 General Procedure for Preparation of 5′-(4-fluorophenyl)-N-(4-(4-methylpiperazin-1-yl)phenyl)-3′-(2,2,2-trifluoroethyl)-1H,3′H-[2,4′-biimidazole]-4-carboxamide ::US11530197, Compound 120
SMILES CN1CCN(CC1)c1ccc(NC(=O)c2c[nH]c(n2)-c2c(ncn2CC(F)(F)F)-c2ccc(F)cc2)cc1
InChI Key InChIKey=GWPJGPNZHSWHEN-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 585274
Affinity DataIC50: 66nMAssay Description:TNIK(h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM RLGRDKYKTLRQIRQ, 10 mM Magnesium Acetate and [gamma-33P-ATP](specific activity a...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:MAP4K4 (h) is incubated with 8 mM MOPS pH 7.0, 0.2 mM EDTA, 250 μM RLGRDKYKTLRQIRQ, 10 mM Magnesium Acetate and [gamma-33P-ATP](specific activit...More data for this Ligand-Target Pair
Affinity DataIC50: 66nMAssay Description:The required volume of the 50× stock of test compound was added to the assay before a reaction mix containing the enzyme and substrate was added. The...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:The required volume of the 50× stock of test compound was added to the assay before a reaction mix containing the enzyme and substrate was added. The...More data for this Ligand-Target Pair