BDBM585066 US11529347, Compound 44

SMILES Clc1ccccc1-c1n[nH]c2nc(cnc12)N1CC2CNCC2C1

InChI Key InChIKey=WOSJZPFYZCQLQE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 585066   

TargetTyrosine-protein phosphatase non-receptor type 11(Human)
Relay Therapeutics

US Patent
LigandPNGBDBM585066(US11529347, Compound 44)
Affinity DataIC50: 1.00E+4nMAssay Description:SHP2 is allosterically activated through binding of bis-tyrosyl-phosphorylated peptides to its Src Homology 2 (SH2) domains. The latter activation st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2023
Entry Details
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