BDBM584242 (2R,3S,4R,5R)-2-((R)- bicyclo[4.2.0]octa-1(6),2,4-trien-3- yl(hydroxy)methyl)-5-(4-vinyl-7H- pyrrolo[2,3-d]pyrimidin-7- yl)tetrahydrofuran-3,4-diol::US11524962, Example 46

SMILES O[C@@H]([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(C=C)ncnc12)c1ccc2CCc2c1

InChI Key InChIKey=AIEVSAJVTONOEJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 584242   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM584242((2R,3S,4R,5R)-2-((R)- bicyclo[4.2.0]octa-1(6),2,4-...)
Affinity DataIC50: 2.06E+3nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
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