BDBM584238 (2R,3S,4R,5R)-2-((R)- bicyclo[4.2.0]octa-1,3,5-trien-3- yl(hydroxy)methyl)-5-(4-butyl-7H- pyrrolo[2,3-d]pyrimidin-7- yl)tetrahydrofuran-3,4-diol::US11524962, Example 42

SMILES CCCCc1ncnc2n(ccc12)[C@@H]1O[C@H]([C@H](O)c2ccc3CCc3c2)[C@@H](O)[C@H]1O

InChI Key InChIKey=QWRZSUKPGBUDGK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 584238   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM584238((2R,3S,4R,5R)-2-((R)- bicyclo[4.2.0]octa-1,3,5-tri...)
Affinity DataIC50: 392nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
Go to US Patent