BDBM584235 (2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo [2,3-d]pyrimidin-7-yl)-5-((S)-1- (bicyclo[4.2.0]octa-1(6),2,4-trien-3-yl)- 1-hydroxyethyl)tetrahydrofuran-3,4- diol::US11524962, Example 39

SMILES C[C@@](O)([C@H]1O[C@H]([C@H](O)[C@@H]1O)n1ccc2c(N)ncnc12)c1ccc2CCc2c1

InChI Key InChIKey=SVJLKRXTYXVBPP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 584235   

TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics

US Patent
LigandPNGBDBM584235((2R,3R,4S,5S)-2-(4-amino-7H- pyrrolo [2,3-d]pyrimi...)
Affinity DataIC50: 1.24E+3nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/13/2023
Entry Details
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