BDBM584225 (2R,3S,4R,5R)-2-((R)- bicyclo[4.2.0]octa-1(6),2,4-trien-3- yl(hydroxy)methyl)-5-(4-methyl-7H- pyrrolo[2,3-d]pyrimidin-7- yl)tetrahydrofuran-3,4-diol::US11524962, Example 11::US11524962, Example 44
SMILES Cc1ncnc2n(ccc12)[C@@H]1O[C@H]([C@H](O)c2ccc3CCc3c2)[C@@H](O)[C@H]1O
InChI Key InChIKey=GIVBMSCEMGCGQJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 584225
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 6.80nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 3nMAssay Description:HotSpot Assay. Compounds were solubilized and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (50 mM Tr...More data for this Ligand-Target Pair
TargetMethylosome protein 50/Protein arginine N-methyltransferase 5(Human)
Prelude Therapeutics
US Patent
Prelude Therapeutics
US Patent
Affinity DataIC50: 23.7nMAssay Description:Compounds were solubilized, and 3-fold diluted in 100% DMSO. These diluted compounds were further diluted in the assay buffer (20 mM Tris-HCl, pH 8.0...More data for this Ligand-Target Pair