BDBM58376 3-[3-(4-chlorophenyl)-5-methyl-7-oxidanylidene-furo[3,2-g]chromen-6-yl]propanoic acid::3-[3-(4-chlorophenyl)-5-methyl-7-oxo-6-furo[3,2-g][1]benzopyranyl]propanoic acid::3-[3-(4-chlorophenyl)-5-methyl-7-oxofuro[3,2-g]chromen-6-yl]propanoic acid::3-[3-(4-chlorophenyl)-7-keto-5-methyl-furo[3,2-g]chromen-6-yl]propionic acid::MLS001165376::SMR000540072::US20230364057, Compound 25::cid_1792822

SMILES Cc1c(CCC(O)=O)c(=O)oc2cc3occ(-c4ccc(Cl)cc4)c3cc12

InChI Key InChIKey=GMCMEYZNEXEIDX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 58376   

TargetStreptokinase A(Streptococcus pyogenes M1 GAS)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM58376(3-[3-(4-chlorophenyl)-5-methyl-7-oxidanylidene-fur...)
Affinity DataEC50:  1.50E+5nMAssay Description:Keywords: Group A streptococcus, GAS, streptokinase, expression, virulence, inhibition, dose response, EC50 Assay Overview: The goal of this assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/8/2011
Entry Details
PCBioAssay
TargetDNA gyrase inhibitor(Escherichia coli (strain K12))
The Florida International University Board of Trustees

US Patent
LigandPNGBDBM58376(3-[3-(4-chlorophenyl)-5-methyl-7-oxidanylidene-fur...)
Affinity DataIC50: 1.06E+4nMAssay Description:SDFQ HTS primary assay using pAB1_FL905 was performed in 2 µL of (1 xDNA gyrase buffer: 20 mM Tris-Acetate pH 7.9, 50 mM KAc, 10 mM MgCl2, 2 mM DTT, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2024
Entry Details
Go to US Patent