BDBM582634 WO2023288264, Compound 25

SMILES C[C@@H]1OC(=O)c2ccc(Nc3cc4c(cnc(OC5CC5)c4cn3)[C@@](C)(O)C3CC3)nc2[C@H]1C

InChI Key InChIKey=LDBXVCUBYJAIPD-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582634   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Blueprint Medicines

WIPO

LigandBDBM582634(WO2023288264, Compound 25)Copy SMILESCopy InChI

Affinity DataIC50: 27nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details
Copy Entry DOIWIPO WO2023288264

Copy Rxn URL