BDBM582618 WO2023288264, Compound 10

SMILES COc1ncc(c2cc(Nc3ccnc(n3)N3CCC[C@@H]3C)ncc12)C(C)(C)O

InChI Key InChIKey=ROLRCLYYBIXIHR-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582618   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Blueprint Medicines

WIPO

LigandBDBM582618(WO2023288264, Compound 10)Copy SMILESCopy InChI

Affinity DataIC50: 1.19nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/5/2023
Entry Details
Copy Entry DOIWIPO WO2023288264

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