BDBM582608 WO2023288264, Compound 4::WO2023288264, Compound 5::WO2023288264, Compound 6

SMILES COc1ncc(c2cc(Nc3ccnc(n3)C(C)(C)F)ncc12)C(C)(C)O

InChI Key InChIKey=ONKRWGYFLNUCNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 582608   

LigandPNGBDBM582608(WO2023288264, Compound 4 | WO2023288264, Compound ...)
Affinity DataIC50: 2.34nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
WIPO WO2023288264

LigandPNGBDBM582608(WO2023288264, Compound 4 | WO2023288264, Compound ...)
Affinity DataIC50: 18nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
WIPO WO2023288264

LigandPNGBDBM582608(WO2023288264, Compound 4 | WO2023288264, Compound ...)
Affinity DataIC50: 9.23nMAssay Description:Inhibitors were dissolved in 100% DMSO at a stock concentration of 10 mM. A 100X, 10-point, 4-fold serial dilution of each inhibitor was created in 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details
WIPO WO2023288264