BDBM582529 US11524945, Compound Erlotinib-4-methylphenyl analog (E4ME)

SMILES COCCOc1cc2ncnc(Nc3ccc(C)c(c3)C#C)c2cc1OCCOC

InChI Key InChIKey=PENVNSXCNXIPIF-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 582529   

TargetIntegrin-linked protein kinase(Human)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM582529(US11524945, Compound Erlotinib-4-methylphenyl anal...)
Affinity DataKd:  1.55E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM582529(US11524945, Compound Erlotinib-4-methylphenyl anal...)
Affinity DataKd:  745nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent