BDBM582528 US11524945, Compound Gefitinib

SMILES COc1cc2ncnc(NC3=CC(Cl)C(F)C=C3)c2cc1OCCCN1CCOCC1

InChI Key InChIKey=YWEAQFVLBUGCSC-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 582528   

TargetIntegrin-linked protein kinase(Human)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM582528(US11524945, Compound Gefitinib)
Affinity DataKd:  4.51E+3nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor(Human)
The Cleveland Clinic Foundation

US Patent
LigandPNGBDBM582528(US11524945, Compound Gefitinib)
Affinity DataKd:  110nMAssay Description:Thus, while these compounds were extensively used in studying ILK-mediated cellular and disease processes, their reported inhibitory effects are prob...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2023
Entry Details
Go to US Patent