BDBM582493 US11518779, Compound 21

SMILES Nc1nc(=O)n(cc1CSCCC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12)[C@H]1C[C@H](O)[C@@H](CO)O1

InChI Key InChIKey=VBHJTRJFKDJUNR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 582493   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Victoria Link

US Patent
LigandPNGBDBM582493(US11518779, Compound 21)
Affinity DataIC50: 3.60E+3nMAssay Description:The DNMT1 assays were carried to determine the IC50 with transition state analogs. The reaction (100 μL) containing 50 mM Tris-HCl pH 8.0, 100 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2023
Entry Details
Go to US Patent