BDBM581994 WO2023287730, Compound P171-1.5

SMILES CC(C)c1nnc2nc(N[C@H](C)c3cccc(c3)C(F)(F)F)c3CN(Cc3n12)C(=O)C12CC(C1)C2

InChI Key InChIKey=UUBFAXDGJXYDHW-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 581994   

LigandPNGBDBM581994(WO2023287730, Compound P171-1.5)
Affinity DataIC50: 15nMAssay Description:Reaction buffer was prepared with 10 mM HEPES 7.4, 150 mM NaCl, 5 mM MgCl2, 1 mM DTT, 0.05% BSA, 0.0025% NP40, and 0.5% DMSO. Recombinant KRAS G12C p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/2/2023
Entry Details
WIPO WO2023287730